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Clotrimazole
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It is used to treat skin infections, like – tinea cruris (jock itch), tinea pedis (athlete’s foot), candidiasis (various yeast infections of the mucous membranes and skin), ringworm (tinea corporis), tinea versicolor (patches of skin which are different in color than the rest of the skin), and infected diaper rash.
Mechanism of Action
This medicine works by blocking the growth of fungus (yeast) which causes the infection.
It does this by stopping the yeast from producing ergosterol, a sterol molecule that is an important component of fungal cell membranes (there are essential for yeast survival). Disruption of ergosterol production leads to holes in the fungal cell membrane.
This medication is available for purchase without a prescription at pharmacies and other retail outlets (these are used to treat yeast infections of the vagina and the skin).
However, it is also available on prescription (this form is used to treat yeast infections of the skin and mouth).
It comes as a lotion, cream, solution, and powder, that can be applied to the skin; vaginal cream and vaginal tablets to be inserted into the vagina; lozenges to dissolve in the mouth.
Dosage
Before and after using this medicine, you should wash your hands and make sure the target area is dry and clean. The lotion, cream, or solution is applied to the affected skin areas, two times per day (in the morning and evening).
These vaginal creams should be inserted via applicator once per day, recommended at night, for a week.
Side Effects And Precautions
When applied to the skin, this medicine can cause some allergic reactions, such as – hives, skin rash, swelling of the lips, face, or tongue as well as burning and redness as side effects.
It is usually considered safe to use by pregnant women. Currently, there are no studies linking the use of this medication on pregnant women and earlier birth or a higher chance of a baby having low birth weight.
Pregnancy & Breastfeeding
If a pregnant woman uses it to treat vaginal thrush, it is recommended that she inserts it with the fingers rather than with the applicator provided.
Also, it is not known precisely whether this medicine can pass into breast milk. Therefore, do not take it without first talking to your healthcare professional if you are breast-feeding a baby.
Additionally, do not give this medication to a child younger than 12 years old without your doctor’s advice.
Alcohol
There are no known interactions between this antifungal and alcohol intake.
Miconazole
It is an antifungal agent that has an antimicrobial activity for use in the local treatment of fungal infections.
It comes as a mouth gel, cream, vaginal pessaries, and vaginal cream. This medicine is from the same family of solutions as itraconazole, ketoconazole, or fluconazole, which are used mostly in yeast diseases.
Mechanism of Action
This medicine inhibits the synthesis of ergosterol, a primary component of yeast cell membranes.
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This interferes with membrane-bound enzymes and with the barrier function of the membrane. In addition, it may alter fungal adherence, inhibit catalase systems, and inhibit the formation of mycelia and germ tubes.
Dosage
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The dose of this antifungal medicine is different for different sufferers. Therefore, you should follow the directions on the label or your healthcare specialist’s orders.
The applicator of the cream form should be inserted into the vagina for one week (recommended at night) to treat vaginal yeast infections.
If the signs and symptoms do not improve after 3 days and last for more than a week, contact your healthcare professional at once.
Side Effects
It can cause side effects, including – fever, burning or irritation of the vaginal skin, stomach foul-smelling vaginal discharge, and pain.
Also, this medication has a risk for women who are taking the blood thinner warfarin. It is contraindicated in girls under the age of 12.
Drug Interactions
It may interact with the following drugs:
- warfarin;
- fluconazole.
Clotrimazole vs Miconazole – Which Is More Effective For Treating Yeast Infections?
These medicines are quite similar to antifungals and, typically, healthcare professionals use them interchangeably. Both inhibit the ergosterol biosynthesis, thereby causing disturbances in the function and permeability of the cell membrane.
Both are considered very useful, especially for minor fungal infections, with only the area of infections to determine which product gets used.
Natural Remedies for Yeast Infections
Apple Cider Vinegar
ACV has many benefits and can be used both externally and internally. To use it, you may soak cotton balls in ACV and apply them directly to the rashes.
This procedure should be repeated daily until the infection is gone completely. Also, ACV can be consumed orally along with warm water.
Coconut oil
It has natural antifungal properties that make coconut oil one of the most known foods which help patients with candida problems.
That is because of its lauric acid content, a compound that has potent antifungal and antibacterial properties.
To get rid of yeast infections, you may apply coconut oil to the affected skin three times per day. Moreover, you can combine coconut oil with cinnamon oil for faster results.
Garlic
This vegetable is one of nature’s fantastic “drugs” which has a variety of health benefits, such as – reduced LDL and total cholesterol levels and lowered blood pressure.
Garlic can be used to treat a severe yeast infection by taking a clove of garlic and place it inside of the vagina, according to a 2003 article issued in “Midwifery Today.”
Salt Baths
Salt is an excellent deodorizer and cleanser. To treat yeast infections, only use Himalayan pink rock salt or natural sea salt.
Tea Tree Oil
This essential oil is a renowned home remedy for vaginal yeast infections. For this, soak an organic cotton tampon in 3 drops of this essential oil, diluted in vegetable oil.
Insert this natural remedy in the vagina and leave it in overnight.
Cranberries
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These fruits have strong antifungal and antibacterial properties which can help to fight the fungi causing a yeast infection.
This is due to a substance that helps prevent bacteria from clinging to mucous membranes including the intestines, mouth, and urinary tract.
Gentian Violet
Gentian violet has potent anti-fungal qualities which make it useful in the treatment of yeast infections. It is commonly used to treat breastfeeding mamas and babies with thrush.
Note
Some foods, like wine, beer, milk, cheese, ice cream, are strongly associated with candida. If you suffer from recurring yeast infections, it is recommended to eliminate these foods from your regular nutrition.
However, foods high in vitamin C boost your immune system and help prevent these types of infections.
Images credit – Shutterstock
READ THIS NEXT:Facts About Trichomoniasis
What is poison ivy?
Poison ivy is a common poisonous plant that causes an itchy skin rash. Other rash-inducing poisonous plants include poison oak and poison sumac. These plants produce an oily sap called urushiol that brings on an irritating, itchy allergic reaction. When you touch a poisonous plant or an object that’s been in contact with a plant, you develop an itchy rash. This rash is a form of allergic contact dermatitis.
How common is a poison ivy rash?
Up to 90% of people who come into contact with poison ivy oil develop an itchy rash. You don’t have to be exposed to much: 50 micrograms of urushiol — an amount smaller than a grain of salt — is enough to cause a reaction.
Who might get a poison ivy rash?
Nearly everyone who touches urushiol gets a poison ivy rash. You’re more likely to come into contact with a poisonous plant if you have one of these jobs or hobbies:
- Camper or hiker.
- Farmer or gardener.
- Groundskeeper or landscaper.
- Forestry worker.
- Forest firefighter.
- House painter.
- Roofer.
What do poisonous plants look like?
Poisonous plants grow all over the continental United States. Each type has a distinctive appearance:
- Poison ivy: Poison ivy is most known for its leaves. Each leaf has three leaflets. A popular saying is, “Leaves of three, let them be.” Poison ivy grows as a shrub and a vine. Its summer-green leaves turn reddish in the spring and yellow, orange or red in the fall. A poison ivy shrub may have white berries.
- Poison oak: The leaves have three leaflets like poison ivy, but with rounded tips. The leaves’ undersides are fuzzy and lighter in color than the top. Poison oak grows as a shrub. It’s most common in the western United States. The shrub sometimes has white or yellow berries.
- Poison sumac: This tall shrub or small tree has drooping clusters of green berries. (Nonpoisonous sumacs have red, upright berries. Contact with nonpoisonous sumacs won’t cause an allergic rash.) Each leaf has clusters of seven to 13 smooth leaflets arranged in pairs. Poison sumac thrives in wet, swampy regions.
What causes a poison ivy rash?
Poison ivy, poison oak and poison sumac produce an oil called urushiol. Almost everyone is allergic to this oil. When your skin touches the oil, an allergic reaction occurs. The itchy rash that develops is a type of allergic contact dermatitis.
What are the symptoms of a poison ivy rash?
Urushiol oil causes the same allergic reaction — an itchy skin rash — no matter what poisonous plant you touch. Depending on your skin’s sensitivity, a rash may develop within a few hours or days after initial contact. Symptoms include:
- Blisters.
- Itchy skin rash.
- Redness and swelling.
How is a poison ivy rash diagnosed?
Your healthcare provider will look at the rash, assess your symptoms and ask questions to determine if you could have encountered a poisonous plant. Other allergens and irritants besides poisonous plants can cause contact dermatitis or an itchy rash. If you haven’t been outdoors or in contact with plants, your healthcare provider will want to rule out other skin conditions or causes.
How is a poison ivy rash managed or treated?
Rashes from poisonous plants usually go away within a week or two. In the meantime, these over-the-counter medications can relieve the itchy rash:
- Anti-itch creams, including calamine lotion (Caladryl®) and hydrocortisone creams (Cortizone®).
- Antihistamines, such as diphenhydramine (Benadryl®).
- Colloidal oatmeal baths (Aveeno®) and cold compresses to soothe itching.
Your healthcare provider may prescribe an oral steroid, such as prednisone, if the rash becomes more severe or the rash forms on the mucous membranes of the eyes, nose, mouth or genitals.
What are the complications of poison ivy exposure?
Some situations increase your risk of problems if you’re exposed to poison ivy, poison oak or poison sumac. These factors include:
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- Inhaling smoke: When poisonous plants burn, they release urushiol into the air. You may develop a rash inside of your nasal passages, mouth and throat from inhaling the smoke. Oil in the air also affects the lungs and can cause serious breathing problems.
- Scratching: It’s hard not to scratch this itchy rash. But you can get an infection if you scratch until skin bleeds. Bacteria from under your fingernails can get inside any open wound.
Can a poison ivy rash spread to other parts of the body?
No. It might look like a rash is spreading, but you’re actually developing new rashes on areas of skin that came into contact with urushiol oil. You might have touched a plant in some areas and not even realized it — for example, if a backpack strap brushed against plants and then touched your bare shoulder. Some rashes take longer to develop. The extent of the rash depends on your skin sensitivity and how much oil you touched.
Is a poison ivy rash contagious?
You can’t get a poison ivy rash by touching another person’s rash. But you could develop a rash if you touch the oil on another person’s body or clothes. You can also come in contact with the oil by touching your pet’s fur or a contaminated item like a gardening tool or camping gear.
How can I prevent a poison ivy rash?
The best way to avoid developing this itchy rash is by learning what poisonous plants look like so you can avoid them.
If you think you’ve come in contact with a poisonous plant, you can:
- Apply isopropyl (rubbing) alcohol to exposed body parts, gardening tools or other contaminated items to strip away the oil.
- Scrub under your fingernails with a brush.
- Use dishwashing soap and cool water to wash hands that have touched a poisonous plant.
- Wash clothes after being outdoors.
- Wear long sleeves, pants and gloves when doing yard work, gardening, farming or hiking.
- Wear rubber gloves while bathing pets that have been in contact with poisonous plants.
What is the prognosis (outlook) for people with a poison ivy rash?
Most poison plant rashes cause mild (but annoying) symptoms that go away within a week or two. Rarely, a skin rash lasts for longer than a month. Try not to scratch. Scratching can break open skin and cause an infection.
When should I call the doctor?
Reach out to your healthcare provider if you have a poison plant rash and you experience:
- Rash covering more than a quarter of your body.
- Rash on the mucous membranes of the eyes, nose, mouth or genitals.
- Red streaks, fever or other signs of infection.
- Signs of anaphylaxis, including breathing difficulties, hives and swelling.
What questions should I ask my doctor?
If you have a poison plant rash, you may want to ask your healthcare provider:
- Do I need any testing to confirm the rash is from a poisonous plant?
- How can I avoid getting this rash again?
- How can I keep my family members from getting this rash?
- What treatments can I use to reduce itching?
- How long will the rash last?
- Should I look out for signs of complications?
A note from Cleveland Clinic
It’s hard not to scratch an itchy poison ivy rash. Fortunately, most rashes clear up with minimal treatment within a week. Ask your healthcare provider for suggestions to stop the itch. And remember, don’t scratch! You might temporarily feel better, but scratching can introduce bacteria into the skin and cause an infection.